Viewing entries tagged
Auvi-Q

Comment

Emerging Epidemic: Latest Research on Childhood Food Allergies Shows Troubling Trend

eye-for-ebony-415494-unsplash.jpg

We like to follow research in the food allergy world closely—after all, many of our team members are as personally vested as we are professionally in the advancement of food allergy research! Several of our senior team members either have food allergies or have children with food allergies. 

Last month at FABlogCon, we learned that Dr. Ruchi Gupta and her team at Northwestern University were soon releasing a new study in PediatricsThe Public Health Impact of Parent-Reported Childhood Food Allergies in the United States.

The study was published this month, and we wanted to share some key findings with you: 

  • Food allergies continue to affect a significant number of children in the United States—7.6 percent, or nearly 6 million kids, have a food allergy. Of those, 40 percent report having multiple food allergies.

  • Food allergies have a meaningful impact on families—42 percent reported a severe allergic reaction to their food allergen, and nearly 1 in 5 reported that their child had visited the emergency department for a food-allergic reaction in the past year!

  • Not everyone has emergency medicines at the ready—less than half of parents reported that their child has a current prescription for an epinephrine auto-injector, the only treatment for anaphylaxis. 

This study is a continuation of the work carried out by Dr. Gupta and her team in 2011. Their objective was to better assess the public health impact on childhood food allergies. They surveyed over 40,000 households using advanced statistical modeling to ensure they captured a representative sample of children in the United States. 

One noteworthy feature of this study was a “stringent symptom” methodology, which looked at the frequency, type, and severity of allergy symptoms as part of a diagnosis. This approach helped filter out those who did not likely have a food allergy, as several parents reported a food allergy when the symptoms were more characteristic of a food intolerance or oral allergy syndrome (OAS).

Even after applying the stricter criteria, food allergies are still a significant problem for American children. Today, 1 in 13 kids has a food allergy, which translates to 2 in every classroom. Peanut (2.2%) and milk (1.9%) are the most commonly reported food allergies, affecting 1.6 million and 1.4 million children, respectively. African American children are also more likely to have a food allergy than non-Hispanic white children and are more likely than other children to have multiple food allergies. 

Dr. Gupta (second from the left on the bottom row) and her SOAAR research team (Science and Outcomes of Allergy and Asthma Research) at Northwestern University.

Dr. Gupta (second from the left on the bottom row) and her SOAAR research team (Science and Outcomes of Allergy and Asthma Research) at Northwestern University.

We appreciate the work of Dr. Gupta and her team to increase awareness of the public health implications of food allergies. To quote from the study: “With the growing epidemic and life-threatening nature of food allergies, developing treatments and prevention strategies are critical.” 

We couldn’t agree more!

- Susannah & the Allergy Amulet Team 


Comment

Comment

Take Two: The Importance of Carrying Two Epinephrine Auto-injectors

With Halloween around the bend, we wanted to share a quick PSA on the importance of carrying two epinephrine auto-injectors in case of an allergic reaction. 

Why? Let’s look at the facts.

In cases of severe anaphylaxis, one dose of epinephrine is often not enough. Up to 20% of people who receive an initial dose of epinephrine for anaphylaxis require a second injection. This can happen even without further exposure to the allergenic trigger! A second allergic reaction called biphasic anaphylaxis can occur between 1 to 72 hours (typically eight hours) after the initial reaction.

Despite these harrowing stats, most individuals do not carry two auto-injectors.

In a study of roughly 1,000 US patients and caregivers with epinephrine prescriptions, 82% said they do not carry two auto-injectors. Meanwhile, 75% of respondents reported previously administering epinephrine. Of those that sought emergency care, 45% did so because a second dose of epinephrine was unavailable. 

Education and awareness is also lacking. Only a quarter of respondents reported that they were advised to carry two auto-injectors.

But epinephrine is expensive.

We hear you. Epinephrine auto-injectors are not cheap, which can make it difficult to have multiple epinephrine auto-injectors on your person at all times.  

Fortunately, that’s starting to change. Increased market competition and PR scandals like the one that rocked Mylan have helped drive down the price. 

Additionally, below are some cost-saving options worth checking out. 

-      Check for discount codes and savings plans on manufacturer websites. 

-      Purchase generic epinephrine alternatives.

-      Explore mail-order pharmacy options (you may be able to receive a larger supply of medication at a lower co-pay amount if these benefits apply).

-      Price shop between local pharmacies—prices vary, especially between large chains and small pharmacies.

-      Ask your doctor about patient assistance programs. 

-      Switch to your insurance carrier’s “preferred” auto-injector (if applicable).

-      Double check that your pharmacy has applied all possible coupons at check out.

-      Ask your company’s HR department if they offer financial assistance to employees to cover prescriptions.

We hope you all have a SWEET and SAFE Halloween! And don’t forget to TAKE TWO!

-      Meg and the Allergy Amulet Team

Comment

Comment

Why the Thigh?

daryn-stumbaugh-400834.jpg

Most people that carry epinephrine to treat serious allergic reactions will tell you they were given strict instructions to inject the needle into their outer thigh. They may also tell you that the needle can be injected over clothing, if necessary.

For years I carried epinephrine because I received weekly seasonal allergy injections. Today I carry epinephrine for my food-allergic child. For a long time I didn’t know why I was advised to inject the needle into my thigh. My hunch is that most people don’t know why either.

Several years ago, the Journal of Allergy and Clinical Immunology published a study measuring epinephrine absorption in children with a history of anaphylaxis. The participants were randomly assigned to receive a single injection of epinephrine either subcutaneously (under the skin) or intramuscularly (in muscle).

Among children that received epinephrine subcutaneously, epinephrine absorption was considerably slower than for those that received the injection intramuscularly. 

Screen Shot 2017-12-14 at 8.41.17 PM.png

A few years later, the same clinical journal published this study. Their goal was to measure epinephrine absorption in adults intramuscularly versus subcutaneously, but also evaluate absorption differences between two different intramuscular sites: the thigh and the upper arm.

The results of this latter study (below) support the recommendation that epinephrine should be administered in the outer thigh. Greater blood flow in the thigh was considered the likely reason why the absorption rate was higher relative to the upper arm. 

Screen Shot 2017-12-14 at 8.23.41 PM.png

Failure to timely administer epinephrine during an allergic reaction is the leading cause of fatalities among the food allergic, which is why it’s so important to carry epinephrine if you have a food allergy. These findings further underscore the importance of administering the needle into the thigh, as delayed epinephrine absorption could have serious implications during life-threatening episodes of anaphylaxis.

So now you know, folks! Raise your epinephrine high to the sky, then swing it firmly into the thigh!

- Meg and the Allergy Amulet Team 

Comment